Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trialMichel Seymour, Richard Stephens, Anthony Maraveyas et al.|The Lancet|2007Cited by 570
Panitumumab and irinotecan versus irinotecan alone for patients with KRAS wild-type, fluorouracil-resistant advanced colorectal cancer (PICCOLO): a prospectively stratified randomised trialMichel Seymour, Philip Quirke, Sarah Brown et al.|The Lancet Oncology|2013Cited by 392
A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: Results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO)Gary Middleton, Michel Seymour, Sarah Brown et al.|European Journal of Cancer|2013Cited by 24
6097 POSTER Ciclosporin in Combination With Irinotecan for Chemoresistant Advanced Colorectal Cancer – Results of PICCOLO, a Large Randomised Trial With Prospective Molecular StratificationGary Middleton, Michel Seymour, Stephen J. Gwyther et al.|European Journal of Cancer|2011Cited by 6