Howard B. Hamilton

Acatalasemia, a rare congenital abnormality characterized by an apparent lack of the enzyme catalase, was first discovered by Takahara and Miyamoto in 1947 (1, 2). The lack of catalase activity in this disease was initially noted in whole blood, but subsequent studies of the tissues of other organs such as the nasal and oral cavities, the pharynx, bone marrow and liver have revealed a similar absence of activity for this enzyme (3-5). Since the initial description of this disease, 38 cases in 17 families have been found and reported in Japan up to April 1959 (6-17); at this writing no reports of acatalasemia have appeared from any other countries of the world.

Journal Article EPIDEMIOLOGIC STUDIES OF CORONARY HEART DISEASE AND STROKE IN JAPANESE MEN LIVING IN JAPAN, HAWAII AND CALIFORNIA: SERUM LIPIDS AND DIET Get access HIROO KATO, HIROO KATO 1Department of Statistics, Atomic Bomb Casualty Commission, Hiroshima, and Hiroshima Branch, Japanese National Institute of HealthHiroshima, Japan Address reprint requests to Dr. Kato, Dept. of Statistics, Atomic Bomb Casualty Commission, 5-2 Hijiyama Park, Hiroshima, Japan 730 Search for other works by this author on: Oxford Academic PubMed Google Scholar JEANNE TILLOTSON, JEANNE TILLOTSON 2National Heart and Lung Institute, Clinical Applications ProgramBethesda, Maryland Search for other works by this author on: Oxford Academic PubMed Google Scholar MILTON Z. NICHAMAN, MILTON Z. NICHAMAN 3Nutrition Program, Center for Disease ControlAtlanta, Georgia Search for other works by this author on: Oxford Academic PubMed Google Scholar GEORGE G. RHOADS, GEORGE G. RHOADS 4Honolulu Heart Study, Honolulu, Hawaii Search for other works by this author on: Oxford Academic PubMed Google Scholar HOWARD B. HAMILTON HOWARD B. HAMILTON 5Department of Clinical Laboratories, Atomic Bomb Casualty CommissionHiroshima, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar American Journal of Epidemiology, Volume 97, Issue 6, June 1973, Pages 372–385, https://doi.org/10.1093/oxfordjournals.aje.a121518 Published: 01 June 1973 Article history Received: 15 January 1973 Published: 01 June 1973