John Z. Montgomerie

Journal Article Pyogenic Vertebral Osteomyelitis: Report of Nine Cases and Review of the Literature Get access Francisco L. Sapico, Francisco L. Sapico Search for other works by this author on: Oxford Academic PubMed Google Scholar John Z. Montgomerie John Z. Montgomerie Search for other works by this author on: Oxford Academic PubMed Google Scholar Reviews of Infectious Diseases, Volume 1, Issue 5, September-October 1979, Pages 754–776, https://doi.org/10.1093/clinids/1.5.754 Published: 01 September 1979 Article history Received: 06 February 1979 Revision received: 26 April 1979 Published: 01 September 1979

Viral infections and clinical complications were studied during hemodialysis and after renal transplantation. Active cytomegalovirus infection developed in 96% of patients after renal transplantation; reactivation of herpes simplex, varicella-zoster, and Epstein-Barr viruses was found in 35%, 24%, and 0% of patients, respectively. Cytomegalovirus viremia developed in 42% of patients an average of two months after renal transplantation, lasted 1.75 (+/- 1.5) months (except in one patient with chronic viremia), and was followed by chronic viruria. Higher titers of infectious cytomegalovirus were found in the polymorphonuclear than in the mononuclear leukocyte fraction. Reactivation of a latent infection and, less likely, respiratory infection appear to be the most probable mechanisms of cytomegalovirus infection after renal transplantation. One to three months after transplant, cytomegalovirus infection may be related to fever, arthralgia, pneumonitis, and leukopenia; three to four months after transplant, the virus may be related to hepatitis; and 12-30 months after transplant, it may be related to retinitis in patients with chronic viremia. Although other causes of these complications are possible, herpes simplex virus, Epstein-Barr virus, varicella-zoster virus, measles virus, adenovirus, hepatitis B virus, and Toxoplasma gondii appear to be of lesser importance than cytomegalovirus in this respect.

EDWARDS, JOHN E. Jr. M.D.; FOOS, ROBERT Y. M.D.; MONTGOMERIE, JOHN Z. M.R.A.C.P.; GUZE, LUCIEN B. M.D. Author Information

Erythrodermic Skin Diseases-Fox et al. MEDIBALJOURNAL has shown that this can stimulate non-shivering thermogenesis in man. Cold-adapted subjects also showed an increased calorigenic action of noradrenaline Shivering tends to disappear in the cold-adapted subject, and this may explain why all except one of our patients with a relative hypothermia failed to shiver.