Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activityLeslie W. Tari, John Finn, Felice C. Lightstone et al.|Bioorganic & Medicinal Chemistry Letters|2012Cited by 118
Tricyclic GyrB/ParE (TriBE) Inhibitors: A New Class of Broad-Spectrum Dual-Targeting Antibacterial AgentsLeslie W. Tari, John Finn, Xiaoming Li et al.|PLoS ONE|2013Cited by 104
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activityMicheal Trzoss, Leslie W. Tari, Daniel C. Bensen et al.|Bioorganic & Medicinal Chemistry Letters|2012Cited by 81
Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitorsLeslie W. Tari, Ronald V. Swanson, Isaac Hoffman et al.|Bioorganic & Medicinal Chemistry Letters|2006Cited by 37
Drug–Fc conjugate CD388 targets influenza virus neuraminidase and is broadly protective in miceSimon Döhrmann, Leslie W. Tari, James Levin et al.|Nature Microbiology|2025Cited by 13