Maurice Victor

This book covers broad aspects of clinical neurology necessary fro clinical practice. The organization is unique, starting from patient approach, cardinal manifestations of neurological disease, to specific neruological diseases. New developments in neurology, such as molecular neurology and genetics, are incorporated in this edition. The inherited metabolic, congenital, developmental, and psychiatric disorders are largely emphasized.

In the course of our studies of the neuropathology of alcoholism, which were begun at the Neurological Unit, Boston City Hospital, and have continued in the laboratories of the Neurology Service, Massachusetts General Hospital, two of us (R. D. A. and M. V.) observed three, perhaps four, cases in which the myelin sheaths of all the nerve fibers in the central part of the basis pontis had been destroyed in a single, large, symmetric focus. The nerve cells and axis cylinders were spared for the most part, and the blood vessels were patent and unaffected. There were no signs of inflammation in or near the lesion. The disease had occurred on a background of alcoholism and malnutrition; in the two cases with the largest lesions, it had manifested itself clinically by a pseudobulbar palsy and quadriplegia, leading to death in about 13 and 26 days. In the other two cases

* Professor of Neurology, Western Reserve University, School of Medicine and Chief, Neurology Service, Cleveland Metropolitan General Hospital. Formerly Assistant Clinical Professor of Neurology, Harvard Medical School † Bullard Professor of Neuropathology, Harvard Medical School, and Chief, Neurology Service, Massachusetts General Hospital ‡ Formerly Trainee (Teaching Fellow) in Neuropathology (USPHS Neurology Training Grant TIN B-5075), Harvard Medical School. Presently, Asst. Professor of Neurology, Bowman Gray School of Medicine, Winston-Salem, North Carolina From the Neurology Service and Charles S. Kubik Laboratory for Neuropathology of the Homer Wright Laboratories of the Department of Pathology, Massachusetts General Hospital, and the Department of Neurology (Neuropathology) Harvard Medical School

Journal Article PONTINE AND EXTRAPONTINE MYELINOLYSIS Get access DAVID G. WRIGHT, DAVID G. WRIGHT Divisions of Neuropathology and Neurology, Cleveland Metropolitan General Hospital, and Case Western Reserve University, School of Medicine, ClevelandOhio Search for other works by this author on: Oxford Academic PubMed Google Scholar ROBERT LAURENO, ROBERT LAURENO Divisions of Neuropathology and Neurology, Cleveland Metropolitan General Hospital, and Case Western Reserve University, School of Medicine, ClevelandOhio Search for other works by this author on: Oxford Academic PubMed Google Scholar MAURICE VICTOR MAURICE VICTOR Divisions of Neuropathology and Neurology, Cleveland Metropolitan General Hospital, and Case Western Reserve University, School of Medicine, ClevelandOhio Search for other works by this author on: Oxford Academic PubMed Google Scholar Brain, Volume 102, Issue 2, June 1979, Pages 361–385, https://doi.org/10.1093/brain/102.2.361 Published: 01 June 1979 Article history Received: 03 October 1978 Published: 01 June 1979