Sheffield Teaching Hospitals NHS Foundation Trust
Publishes on Inflammatory mediators and NSAID effects, Neurotransmitter Receptor Influence on Behavior, Receptor Mechanisms and Signaling. 68 papers and 2.7k citations.
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An operant behavioral study on morphine addiction utilized a self-injection technique for giving intravenous injections to relatively unrestrained rats. The rate of self-injection varied inversely with the dose. Morphine was a reinforcer that produced almost immediate satiation.
The intravascular portion was made of silicone rubber, passed down the external jugular vein into the right heart. The remainder was made of polyethylene, brought subcutaneously to the back of the neck. Most cannulas remained functional for many weeks. silicone rubber cannulas Submitted on October 3, 1963