Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 studyEzra E.W. Cohen, Signe Friesland, Nicolas Mach et al.|The Lancet|2018Cited by 1.7k
Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trialJean-Pascal H. Machiels, Ezra E.W. Cohen, Robert I. Haddad et al.|The Lancet Oncology|2015Cited by 394
Afatinib versus methotrexate in older patients with second-line recurrent and/or metastatic head and neck squamous cell carcinoma: subgroup analysis of the LUX-Head & Neck 1 trialPaul M. Clément, Jan B. Vermorken, Thomas Gauler et al.|Annals of Oncology|2016Cited by 45
Phase II study of XR 5000, an inhibitor of topoisomerases I and II, in advanced colorectal cancerFrancesco Caponigro, P. Fumoleau, Christian Dittrich et al.|European Journal of Cancer|2002Cited by 28