Development of SYN-004, an oral beta-lactamase treatment to protect the gut microbiome from antibiotic-mediated damage and prevent Clostridium difficile infectionMichael Kaleko, Sheila Connelly, J. Andrew Bristol et al.|Anaerobe|2016Cited by 71
Oral Metallo-Beta-Lactamase Protects the Gut Microbiome From Carbapenem-Mediated Damage and Reduces Propagation of Antibiotic Resistance in PigsSheila Connelly, Michael Kaleko, Brian Fanelli et al.|Frontiers in Microbiology|2019Cited by 44
SYN-004 (ribaxamase), an oral beta-lactamase, mitigates antibiotic-mediated dysbiosis in a porcine gut microbiome modelSheila Connelly, Michael Kaleko, J. Andrew Bristol et al.|Journal of Applied Microbiology|2017Cited by 41
Distinct consequences of amoxicillin and ertapenem exposure in the porcine gut microbiomeSheila Connelly, Michael Kaleko, Poorani Subramanian et al.|Anaerobe|2018Cited by 35
Low dose oral beta-lactamase protects the gut microbiome from oral beta-lactam-mediated damage in dogsSheila Connelly, Michael Kaleko, Brian Fanelli et al.|AIMS Public Health|2019Cited by 25