Cited by 3.3kOpen Access
BioClinica (United States)
ORCID: 0000-0002-7228-7018Publishes on Lung Cancer Treatments and Mutations, Lung Cancer Diagnosis and Treatment, RNA modifications and cancer. 372 papers and 10.6k citations.
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Recent knowledge on apoptosis has made it possible to devise novel approaches, which exploit this process to treat cancer. In this review, we discuss in detail approaches to induce tumor cell apoptosis, their mechanism of action, stage of development, and possible drawbacks. Finally, the obstacles yet to be overcome and the perspectives for potential clinical use of apoptosis-triggering approaches in cancer therapy in the future are assessed.