A

A. Van de Weghe

Ghent University

Publishes on Genetic and phenotypic traits in livestock, Genetic Mapping and Diversity in Plants and Animals, Animal Genetics and Reproduction. 68 papers and 1.2k citations.

68Publications
1.2kTotal Citations

Is this you? Claim your profile.

Add your photo, update your bio, and get notified when your ranking changes.

Top publicationsby citations

A genetic study of four Belgian pig populations by means of seven microsatellite loci
Alex Van Zeveren, L. Peelman, A. Van de Weghe et al.|Journal of Animal Breeding and Genetics|1995
Cited by 51

Summary Genetic variability within four Belgian pig breeds, (Landrace (BL), Negative (BN), Piétrain (P), and Large White (LW)) was investigated using seven microsatellite loci. Differences in allele frequencies indicate each breed's particular identity. Computation of polymorphism information contents (PIC), theoretical heterozygosities, effective numbers of alleles, and probabilities of encountering, at random, two identical individuals in each breed revealed a variability, decreasing in the order LW, BN, BL, and P. Five types of genetic distance between the breeds were also calculated. Two‐by‐two breed comparisons indicated some distances to be rather important, confirming the breeds' morphological differences. BL and BN show the closest resemblance, while P is the most distant breed. The chances of encountering, at random, two identical individuals among two breeds are small, and confirm the conclusions resulting from the genetic distances. The efficiency of the microsatellites in parentage control is high. Zusammenfassung 7 Microsatellitsystemen studiert in 4 Belgische Schweinerassen Anhand von 7 Microsatellitsystemen wurde die genetische Variabilität innerhalb 4 Belgischer Schweinerassen (Landrasse [BL], Negativ [BN], Pietrain [P] und Large White [LW] untersucht. Unterschiede in Allelhäufigkeiten deuten auf die besondere Identität jeder einzelnen Rasse. Berechnung von Polymorphismus, Informationsinhalt (PIC), theoretischer Heterozygotiewerte, wirksamer Anzahl von Allelen und Wahrscheinlichkeit zweier identischer Individuen in jeder Rasse brachte Hinweise auf abnehmende Variabilität in der Reihenfolge von LW, BN, BL und P. Ausserdem wurden 5 Arten genetischer Distanzen zwischen den vier Schweinerassen berechnet. Bei paarweisem Vergleich zeigten diese Distanzen sich als ziemlich gross, so dass damit die morphologischen Differenzen zwischen den Rassen bestätigt werden. BL und BN haben die engste Verwandtschaft und P ist am weitesten entfernt von BL, BN und LW. Die Wahrscheinlichkeit, zufällig zwei identische Tiere in zwei Rassen zu finden, fehlt praktisch und bestätigt die Schlussfolgerungen, die sich aus den genetischen Distanzen ergeben. Die Microsatelliten sind sehr zweckmässig anwendbar in der Abstammungskontrolle.

Characterization of porcine polymorphic microsatellite loci
Wouter Coppieters, A. Van de Weghe, Luc Peelman et al.|Animal Genetics|1993
Cited by 45

Twenty-seven (CA)n and two (GA)n microsatellite clones were isolated out of a size-selected genomic pig library. These were sequenced and the number of uninterrupted dinucleotides was found to range from 12 to 26. Flanking primers were chosen for 11 dinucleotide repeats and optimal conditions for polymerase chain reaction (PCR) amplifications were established. Different microsatellite loci were amplified simultaneously by combining primer sets. Related and unrelated pigs were screened for length polymorphisms of the different microsatellite loci. The polymorphic information content (PIC) of these loci ranged between 0.62 and 0.83. Segregation studies in pig reference families established Mendelian inheritance. Locus S0022 was found to be X-linked.