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Elisa Medeot

Centro de Ingeniería Genética y Biotecnología

Publishes on Muscle Physiology and Disorders, Cardiomyopathy and Myosin Studies, Genetic Neurodegenerative Diseases. 2 papers and 150 citations.

2Publications
150Total Citations

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Top publicationsby citations

Characterization of antibodies directed against the Ankrd2 human muscle protein
Snežana Kojić, Elisa Medeot, Georgine Faulkner|Archives of Biological Sciences|2009
Cited by 3Open Access

In order to study the function of the Ankrd2 protein, for which commercial antibodies are not available, we report the production and analysis of polyclonal antibodies to full-length Ankrd2 and its C-terminal and N-terminal regions, as well as a monoclonal antibody to the C-terminus of the protein. Epitope mapping making use of recombinant deletion mutants showed that an epitope located in region 323-333 aa of Ankrd2 is detected by the monoclonal antibody. The high specificity of all four anti-Ankrd2 antibodies for recombinant and endogenous Ankrd2 protein is also demon?strated.