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Guy G. Poirier

Centre hospitalier universitaire de Québec

ORCID: 0000-0002-4869-1424

Publishes on PARP inhibition in cancer therapy, DNA Repair Mechanisms, Cell death mechanisms and regulation. 432 papers and 41.6k citations.

PubIndex Score98Top 2%How it's scored

🌟#2 Current Senior Leader in PARP inhibition in cancer therapy 🌟#9 Current Senior Leader in Toxin Mechanisms and Immunotoxins

432Publications

41.6kTotal Citations

#2in PARP inhibition in cancer therapy

First publication: 1971First senior author: 1977

PARP inhibition in cancer therapy DNA Repair Mechanisms Cell death mechanisms and regulation Toxin Mechanisms and Immunotoxins Calcium signaling and nucleotide metabolism

Top publicationsby citations

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

Damien D’AMOURS, Guy G. Poirier|Biochemical Journal|1999

Cited by 601

Methods for Biochemical Study of Poly(ADP-Ribose) Metabolism in Vitro and in Vivo

Girish M. Shah, Guy G. Poirier, Serge Desnoyers et al.|Analytical Biochemistry|1995

Cited by 175

Mode of action of poly(ADP-ribose) glycohydrolase

G. Brochu, Guy G. Poirier, Caroline Duchaine et al.|Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression|1994

Cited by 131

PARP-1 Modulation of mTOR Signaling in Response to a DNA Alkylating Agent

Chantal Éthier, Guy G. Poirier|PLoS ONE|2012

Cited by 78

ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance

Julia O’Sullivan, Guy G. Poirier|Nucleic Acids Research|2023

Cited by 13