AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiationAishath Naeem, Ryan F.L. O’Shaughnessy|Cell Death and Differentiation|2015Cited by 72
A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitisAishath Naeem, Ryan F.L. O’Shaughnessy|Journal of Allergy and Clinical Immunology|2016Cited by 47
Cutaneous Human Papillomaviruses Down-regulate AKT1, whereas AKT2 Up-regulation and Activation Associates with TumorsRyan F.L. O’Shaughnessy, Carolyn Byrne|Cancer Research|2007Cited by 40
Akt1-associated actomyosin remodelling is required for nuclear lamina dispersal and nuclear shrinkage in epidermal terminal differentiationClare Rogerson, Ryan F.L. O’Shaughnessy|Cell Death and Differentiation|2021Cited by 17
Differential expression of secreted factors <i> <scp>SOSTDC</scp> 1 </i> and <i> <scp>ADAMTS</scp> 8 </i> cause profibrotic changes in linear morphoea fibroblastsIrbaz I. Badshah, Ryan F.L. O’Shaughnessy|British Journal of Dermatology|2018Cited by 15