Computer-Aided Discovery of Aromatic <scp>l</scp>-α-Amino Acids as Agonists of the Orphan G Protein-Coupled Receptor GPR139Vignir Ísberg, David E. Gloriam, Kirsten B. Andersen et al.|Journal of Chemical Information and Modeling|2014Cited by 58
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRWAnne Cathrine Nøhr, Hans Bräuner‐Osborne, I. Sadaf Farooqi et al.|Neurochemistry International|2016Cited by 46
Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and MutantsKasper Harpsøe, David E. Gloriam, Hans Bräuner‐Osborne et al.|Scientific Reports|2015Cited by 41
The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding siteAnne Cathrine Nøhr, David E. Gloriam, Leonard Floryan et al.|Scientific Reports|2017Cited by 32
Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139Mohamed A. Shehata, David E. Gloriam, Christoph Bisig et al.|Scientific Reports|2016Cited by 28