S

Stig Sonne‐Holm

Frederiksberg Hospital

Publishes on Orthopaedic implants and arthroplasty, Hip disorders and treatments, Total Knee Arthroplasty Outcomes. 144 papers and 6.1k citations.

144Publications
6.1kTotal Citations

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Top publicationsby citations

Prevalence of Malformations of the Hip Joint and Their Relationship to Sex, Groin Pain, and Risk of Osteoarthritis
Kasper Gosvig, Steffen Jacobsen, Stig Sonne‐Holm et al.|Journal of Bone and Joint Surgery|2010
Cited by 400

BACKGROUND: Although the clinical consequences of femoroacetabular impingement have been well described, little is known about the prevalence of the anatomical malformations associated with this condition in the general population, the natural history of the condition, and the risk estimates for the development of osteoarthritis. METHODS: The study material was derived from a cross-sectional population-based radiographic and questionnaire database of 4151 individuals from the Copenhagen Osteoarthritis Substudy cohort between 1991 and 1994. The subjects were primarily white, and all were from the county of Østerbro, Copenhagen, Denmark. The inclusion criteria for this study were met by 1332 men and 2288 women. On the basis of radiographic criteria, the hips were categorized as being without malformations or as having an abnormality consisting of a deep acetabular socket, a pistol grip deformity, or a combination of a deep acetabular socket and a pistol grip deformity. Hip osteoarthritis was defined radiographically as a minimum joint-space width of <or=2 mm. RESULTS: The male and female prevalences of hip joint malformations in the 3620 study subjects were 4.3% and 3.6%, respectively, for acetabular dysplasia; 15.2% and 19.4% for a deep acetabular socket; 19.6% and 5.2% for a pistol grip deformity; and 2.9% and 0.9% for a combination of a deep acetabular socket and pistol grip deformity. The male and female prevalences of a normal acetabular roof were 80.5% and 77.0%. We found no significantly increased prevalence of groin pain in subjects whose radiographs showed these hip joint malformations (all p > 0.13). A deep acetabular socket was a significant risk factor for the development of osteoarthritis (risk ratio, 2.4), as was a pistol grip deformity (risk ratio, 2.2). Acetabular dysplasia and the subject's sex were not found to be significant risk factors for the development of hip osteoarthritis (p = 0.053 and p = 0.063, respectively). The prevalence of hip osteoarthritis was 9.5% in men and 11.2% in women. The prevalence of concomitant malformations was 71.0% in men with hip osteoarthritis and 36.6% in women with hip osteoarthritis. CONCLUSIONS: In our study population, a deep acetabular socket and a pistol grip deformity were common radiographic findings and were associated with an increased risk of hip osteoarthritis. The high prevalence of osteoarthritis in association with malformations of the hip joint suggests that an increased focus on early identification of malformations should be considered.

Long-term follow-up of meniscectomy in athletes. A prospective longitudinal study
U. Jørgensen, Stig Sonne‐Holm, Flemming Lauridsen et al.|Journal of Bone and Joint Surgery - British Volume|1987
Cited by 318

We report the results of a prospective longitudinal study of 147 athletes who had had a meniscectomy for an isolated meniscus injury. The patients were reviewed in detail after median periods of 4.5 years and 14.5 years and the results analysed. The frequency of complaints related to the operation increased from 53% at 4.5 years to 67% at 14.5 years, while demonstrable knee instability increased from 10% to 36%. The incidence of radiographic changes of degeneration rose from 40% to 89% and at late review 8% of patients had definite osteoarthritis by the criteria of Ahlbäck (1968). In consequence 46% had given up or reduced their sporting activity, and 6.5% had changed their occupation. Radiographic deterioration started after the 4.5-year review in 49% of the patients and was more frequent after lateral than medial meniscectomy.

Degenerative Lumbar Spondylolisthesis: An Epidemiological Perspective
Cited by 297

In Brief Study Design. A cross-sectional epidemiological survey of 4151 participants of the Copenhagen Osteoarthritis Study. Objective. To identify prevalences and individual risk factors for degenerative lumbar spondylolisthesis. Summary of Background Data. The Copenhagen Osteoarthritis Study has registered health parameters since 1976. In 1993, standardized, lateral radiographs of the lumbar spine were recorded. There were 1533 men and 2618 women. Methods. Statistical correlations were made between degenerative spondylolisthesis, and physical, occupational, and general epidemiological data. Results. A total of 254 cases of lumbar slip were found (males 2.7%, females 8.4%). In females, no significant relationship between age at menopause or childbirths and the presence of degenerative spondylolisthesis were found. In women, relationships between body mass index (BMI) in 1976 and L4 olisthesis (P = 0.001), and between BMI in 1993 and both L4 and L5 olisthesis were found (L4: P = 0.003; L5: P = 0.006). Lumbar lordosis was associated with degenerative spondylolisthesis in women. Occupational exposures to daily lifting or smoking were not associated with degenerative spondylolisthesis. Degenerative spondylolisthesis was associated with increased age in both sexes (L4: P < 0.001; L5: P < 0.001). Conclusions. BMI longitudinally and at index evaluations, age, and angle of lordosis were significantly associated with degenerative spondylolisthesis in women. In men, no individual risk factors for degenerative spondylolisthesis were found, save increased age. We reviewed 4151 randomly selected subjects to identify prevalences and individual risk factors for degenerative lumbar spondylolisthesis. Aging, angle of lumbar lordosis, and increased body mass index were significant risk factors for L4 slips in women. Only increased age constituted a risk factor for lumbar slips in men.

Integrity of the Lateral Femoral Wall in Intertrochanteric Hip Fractures
Henrik Palm, Steffen Jacobsen, Stig Sonne‐Holm et al.|Journal of Bone and Joint Surgery|2007
Cited by 267

BACKGROUND: Reoperations after intertrochanteric fractures are often necessitated by fracture displacement following mobilization of the patient. The biomechanical complexity of the fracture, the position of the implant, and the patient's characteristics are known to influence postoperative outcome. We investigated the importance of an intact lateral femoral wall as a factor in postoperative fracture displacement after fixation with a sliding compression hip screw. METHODS: Two hundred and fourteen consecutive patients with an intertrochanteric fracture were treated with a 135 degrees sliding compression hip screw with a four-hole side-plate between 2002 and 2004. The fractures were classified on preoperative radiographs according to the AO/OTA classification system. The status of the greater and lesser trochanters, the integrity of the lateral femoral wall, and the position of the implant were assessed postoperatively. Reoperations due to technical failure were recorded for six months postoperatively. RESULTS: Only 3% (five) of 168 patients with an intact lateral femoral wall postoperatively underwent a reoperation within six months, whereas 22% (ten) of forty-six patients with a fractured lateral femoral wall were operated on again (p < 0.001). Multivariate logistic regression analyses combining demographic and biomechanical parameters showed a compromised lateral femoral wall to be a significant predictor of a reoperation (p = 0.010). Seventy-four percent (thirty-four) of the forty-six fractures of the lateral femoral wall occurred during the operative procedure itself. A fracture of the lateral femoral wall occurred in only 3% (three) of the 103 patients with an AO/OTA type-31-A1.1, A1.2, A1.3, or A2.1 intertrochanteric fracture compared with 31% (thirty-one) of the ninety-nine with an AO/OTA type 31-A2.2 or A2.3 fracture (p < 0.001). CONCLUSIONS: A postoperative fracture of the lateral femoral wall was found to be the main predictor for a reoperation after an intertrochanteric fracture. Consequently, we concluded that patients with preoperative or intraoperative fracture of the lateral femoral wall are not treated adequately with a sliding compression hip-screw device, and intertrochanteric fractures should therefore be classified according to the integrity of the lateral femoral wall, especially in randomized trials comparing fracture implants.

Hip dysplasia: a significant risk factor for the development of hip osteoarthritis. A cross-sectional survey
Søren Jacobsen, Stig Sonne‐Holm|Lara D. Veeken|2004
Cited by 243Open Access

OBJECTIVES: The aim of this cross-sectional survey of 2232 women and 1336 men (age range 20-91 yr) was to investigate individual risk factors for hip joint osteoarthritis (OA). METHODS: Standardized, weight-bearing pelvic radiographs were evaluated. Radiological hip joint OA was defined as minimum joint space width (JSW) </=2.0 mm. Hip dysplasia was evaluated according to common radiographic indices. Radiographic findings were correlated to general health and lifestyle information obtained at baseline examinations and questionnaires. The study focused on age; self-reported hip pain, occupational exposure to repeated daily lifting, body mass index, smoking and hip dysplasia. RESULTS: Hip dysplasia (HD) prevalence ranged from 5.4-12.8% depending on the radiographic index applied. Hip OA prevalence was 1.0-2.5% in subjects <60 yr of age and 4.4-5.3% in subjects >/=60 yr of age. Of factors entered into logistic regression analyses, only age (P<0.001 for right hips and P<0.001 for left hips) and hip dysplasia (P<0.001 for right hips and P = 0.004 for left hips) were significantly associated with hip OA prevalence in women. In men, only hip dysplasia was associated with hip OA prevalence, P<0.001 in right hips and P = 0.001 in left hips. CONCLUSIONS: Of the individual risk factors investigated in this study, only age and hip dysplasia were associated with the development of hip osteoarthritis.