Cited by 1.7kOpen Access
University of California, Berkeley
Publishes on Genomics and Phylogenetic Studies, RNA and protein synthesis mechanisms, Gene Regulatory Network Analysis. 2 papers and 1.8k citations.
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We describe a novel method for the differential analysis of RNA-Seq data that utilizes bootstrapping in conjunction with response error linear modeling to decouple biological variance from inferential variance. The method is implemented in an interactive shiny app called sleuth that utilizes kallisto quantifications and bootstraps for fast and accurate analysis of RNA-Seq experiments.