Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction MicroscopyRecent advances in far-field fluorescence microscopy have led to substantial improvements in image resolution, achieving a near-molecular resolution of 20 to 30 nanometers in the two lateral dimensions. Three-dimensional (3D) nanoscale-resolution imaging, however, remains a challenge. We demonstrated 3D stochastic optical reconstruction microscopy (STORM) by using optical astigmatism to determine both axial and lateral positions of individual fluorophores with nanometer accuracy. Iterative, stochastic activation of photoswitchable probes enables high-precision 3D localization of each probe, and thus the construction of a 3D image, without scanning the sample. Using this approach, we achieved an image resolution of 20 to 30 nanometers in the lateral dimensions and 50 to 60 nanometers in the axial dimension. This development allowed us to resolve the 3D morphology of nanoscopic cellular structures.
Transmit Subaperturing for Range and Angle Estimation in Frequency Diverse Array RadarWen-Qin Wang, Hing Cheung So|IEEE Transactions on Signal Processing|2014 Different from conventional phased-array, which provides only angle-dependent beampattern, frequency diverse array (FDA) employs a small frequency increment across the antenna elements and results in a range-angle-dependent beampattern. This beampattern offers a potential to localize the targets in two dimensions in terms of slant ranges and azimuth angles. However, it is difficult to obtain the target location information from a standard FDA radar due to the couplings in range and angle responses. In this paper, we propose a transmit subaperturing scheme on the FDA radar for range and angle estimation of targets. The essence is to divide the FDA elements into multiple subarrays and optimize the transmit beamspace matrix with the use of convex optimization. We also discuss several practical issues for designing the FDA radar system parameters. Since the subarrays offer decoupled range and angle responses, the targets can be located using the beamspace-based multiple signal classification algorithm. The range and angle estimation performance is evaluated by comparing with the Cramér-Rao lower bound.
MISC Array: A New Sparse Array Design Achieving Increased Degrees of Freedom and Reduced Mutual Coupling EffectZhi Zheng, Wen-Qin Wang, Yangyang Kong et al.|IEEE Transactions on Signal Processing|2019 Recently, nested and coprime arrays have attracted considerable interest due to their capability of providing increased array aperture, enhanced degrees of freedom (DOFs), and reduced mutual coupling effect compared to uniform linear arrays (ULAs). These features are critical to improving the performance of direction-of-arrival estimation and adaptive beamforming. In this paper, a new sparse array configuration based on the maximum inter-element spacing constraint (MISC) is proposed. The MISC array configuration generally consists of three sparse ULAs plus two separate sensors that are appropriately placed. The MISC array configurations are designed based on the inter-element spacing set, which, for a given number of sensors, is uniquely determined by a closed-form expression. We also derive closed-form expressions for the number of uniform DOFs of the MISC arrays with any number of sensors. Compared with the existing sparse arrays, the MISC array enjoys two important advantages, namely, providing a higher number of DOFs and reducing the mutual coupling effects. Numerical simulations are conducted to verify the superiority of the MISC array over other sparse arrays.
Frequency Diverse Array Antenna: New OpportunitiesWen-Qin Wang|IEEE Antennas and Propagation Magazine|2015 Phased-array antennas are known for their capability to electronically steer a beam with high effectiveness, but beam steering is fixed in an angle for all range cells. This paper reviews frequency diverse array (FDA) antennas. Different from a phased array, an FDA uses a small frequency increment, as compared with the carrier frequency, across array elements. The use of a frequency increment generates an array factor that is a function of the angle, the time, and the range, allowing the FDA antenna to transmit the energy over the desired range and angle. In addition to analyzing FDA factor characteristics, this paper investigates FDA potential applications in range-dependent energy control and technical challenges in system implementation, with an aim to call for further investigations on the FDA.
An Overview on Time/Frequency Modulated Array ProcessingWen-Qin Wang, Hing Cheung So, Alfonso Farina|IEEE Journal of Selected Topics in Signal Processing|2016 Time and frequency modulated arrays have numerous application areas including radar, navigation, and communications. Specifically, a time modulated array can create a beampattern with low sidelobes via connecting and disconnecting the antenna elements from the feed network, while the frequency modulated frequency diverse array produces a range-dependent pattern. In this paper, we aim to introduce these advanced arrays to the signal processing community so that more investigations in terms of theory, methods, and applications, can be facilitated. The research progress of time/frequency modulated array studies is reviewed and the most recent advances are discussed. Moreover, potential applications in radar and communications are presented, along with their technical challenges, especially in signal processing aspects.