Yasuhiro Sorata, Umeo Takahama, Mitsutaka Kimura|Biochimica et Biophysica Acta (BBA) - General Subjects|1984
Cited by 150
Kyushu Dental University
Publishes on Free Radicals and Antioxidants, Photosynthetic Processes and Mechanisms, Antioxidant Activity and Oxidative Stress. 3 papers and 184 citations.
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Abstract— Quercetin(20–100 μ M ) suppressed photohemolysis sensitized by hematoporphyrin, while ascorbate(10–100 μ M ) stimulated it. However, in the presence of 40 μ M quercetin, ascorbate promoted the suppression. The suppression by quercetin was due to scavenging of both singlet oxygen generated by a photosensitized reaction and radicals generated by decomposition of lipid peroxides formed by a singlet oxygen‐dependent reaction. In scavenging, quercetin was oxidized and the oxidation was suppressed by ascorbate. Ascorbate was oxidized by illumination in the presence of quercetin. It is suggested that the cooperation of quercetin with ascorbate in photohemolysis is due to reduction of oxidized quercetin by ascorbate regenerating the flavonol.