The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal DegenerationKow Essuman, Jeffrey Milbrandt, Daniel W. Summers et al.|Neuron|2017Cited by 641
TIR Domain Proteins Are an Ancient Family of NAD+-Consuming EnzymesKow Essuman, Jeffrey Milbrandt, Daniel W. Summers et al.|Current Biology|2018Cited by 257
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletionYo Sasaki, Jeffrey Milbrandt, Takashi Nakagawa et al.|eLife|2016Cited by 206
Structural basis of SARM1 activation, substrate recognition, and inhibition by small moleculesYun Shi, Thomas Ve, Forhad Karim Saikot et al.|Molecular Cell|2022Cited by 142
Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patientsA. Joseph Bloom, Aaron DiAntonio, Xianrong Mao et al.|Molecular Neurodegeneration|2022Cited by 120