Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2Morris E. Feldman, Kevan M. Shokat, Davide Ruggero et al.|PLoS Biology|2009Cited by 1.1k
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinasesBeth Apsel, Zachary A. Knight, Jimmy A. Blair et al.|Nature Chemical Biology|2008Cited by 440
Discovery of Drug-Resistant and Drug-Sensitizing Mutations in the Oncogenic PI3K Isoform p110αEli R. Zunder, Kevan M. Shokat, Zachary A. Knight et al.|Cancer Cell|2008Cited by 97