Accumulation of Mutant α1-Antitrypsin Z in the Endoplasmic Reticulum Activates Caspases-4 and -12, NFκB, and BAP31 but Not the Unfolded Protein ResponseTunda Hidvegi, David H. Perlmutter|Journal of Biological Chemistry|2005Cited by 238
NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanismsAmitava Mukherjee, David H. Perlmutter|Cell Death and Differentiation|2018Cited by 19
Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin DeficiencyJie Li, David H. Perlmutter|Cellular and Molecular Gastroenterology and Hepatology|2024Cited by 2