Role of the C-terminal domain of PCSK9 in degradation of the LDL receptorsØystein L. Holla, Trond P. Leren, Jamie Cameron et al.|Journal of Lipid Research|2011Cited by 63
Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidificationKristian Tveten, Trond P. Leren, Øystein L. Holla et al.|Human Molecular Genetics|2011Cited by 61
Serum levels of proprotein convertase subtilisin/kexin type 9 in subjects with familial hypercholesterolemia indicate that proprotein convertase subtilisin/kexin type 9 is cleared from plasma by low-density lipoprotein receptor–independent pathwaysJamie Cameron, Trond P. Leren, Martin P. Bogsrud et al.|Translational research|2012Cited by 36
Disrupted recycling of the low density lipoprotein receptor by PCSK9 is not mediated by residues of the cytoplasmic domainThea Bismo Strøm, Trond P. Leren, Jamie Cameron et al.|Molecular Genetics and Metabolism|2010Cited by 35
Removal of acidic residues of the prodomain of PCSK9 increases its activity towards the LDL receptorØystein L. Holla, Trond P. Leren, Jon K. Laerdahl et al.|Biochemical and Biophysical Research Communications|2011Cited by 30