Massachusetts General Hospital
ORCID: 0000-0002-5232-6454Publishes on Cancer Immunotherapy and Biomarkers, Urban Transport and Accessibility, Cutaneous Melanoma Detection and Management. 9 papers and 274 citations.
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Artificial intelligence models match or exceed dermatologists in melanoma image classification. Less is known about their robustness against real-world variations, and clinicians may incorrectly assume that a model with an acceptable area under the receiver operating characteristic curve or related performance metric is ready for clinical use. Here, we systematically assessed the performance of dermatologist-level convolutional neural networks (CNNs) on real-world non-curated images by applying computational "stress tests". Our goal was to create a proxy environment in which to comprehensively test the generalizability of off-the-shelf CNNs developed without training or evaluation protocols specific to individual clinics. We found inconsistent predictions on images captured repeatedly in the same setting or subjected to simple transformations (e.g., rotation). Such transformations resulted in false positive or negative predictions for 6.5-22% of skin lesions across test datasets. Our findings indicate that models meeting conventionally reported metrics need further validation with computational stress tests to assess clinic readiness.
This paper proposes a general unplanned incident analysis framework for public transit systems from the supply and demand sides using automated fare collection (AFC) and automated vehicle location (AVL) data. Specifically, on the supply side, we propose an incident-based network redundancy index to analyze the network’s ability to provide alternative services under a specific rail disruption. The impacts on operations are analyzed through the headway changes. On the demand side, the analysis takes place at two levels: aggregate flows and individual responses. We calculate the demand changes of different rail lines, rail stations, bus routes, and bus stops to better understand the passenger flow redistribution under incidents. Individual behavior is analyzed using a binary logit model based on inferred passengers’ mode choices and socio-demographics using AFC data. The public transit system of the Chicago Transit Authority is used as a case study. Two rail disruption cases are analyzed, one with high network redundancy around the impacted stations and the other with low. Results show that the service frequency of the incident line was largely reduced (by around 30%~70%) during the incident time. Nearby rail lines with substitutional functions were also slightly affected. Passengers showed different behavioral responses in the two incident scenarios. In the low redundancy case, most of the passengers chose to use nearby buses to travel further, either to their destinations or to the nearby rail lines. In the high redundancy case, most of the passengers transferred directly to nearby bus or rail lines. The results of the individual analysis show that the increase in network redundancy can increase the probability of using transit during disruptions. This effect is more prominent for low-income passengers. Corresponding policy implications and operating suggestions are discussed.
This paper proposes a general unplanned incident analysis framework for public transit systems from the supply and demand sides using automated fare collection (AFC) and automated vehicle location (AVL) data. Specifically, on the supply side, we propose an incident-based network redundancy index to analyze the network's ability to provide alternative services under a specific rail disruption. The impacts on operations are analyzed through the headway changes. On the demand side, the analysis takes place at two levels: aggregate flows and individual response. We calculate the demand changes of different rail lines, rail stations, bus routes, and bus stops to better understand the passenger flow redistribution under incidents. Individual behavior is analyzed using a binary logit model based on inferred passengers' mode choices and socio-demographics using AFC data. The public transit system of the Chicago Transit Authority is used as a case study. Two rail disruption cases are analyzed, one with high network redundancy around the impacted stations and the other with low. Results show that the service frequency of the incident line was largely reduced (by around 30% ~ 70%) during the incident time. Nearby rail lines with substitutional functions were also slightly affected. Passengers showed different behavioral responses in the two incident scenarios. In the low redundancy case, most of the passengers chose to use nearby buses to move, either to their destinations or to the nearby rail lines. In the high redundancy case, most of the passengers transferred directly to nearby lines. Corresponding policy implications and operating suggestions are discussed.