C.A. Bucholtz

Extensions to a shape-based interpolation method in which pixels that share a boundary edge (one inside and the other outside the object) are considered to be at a distance between adjacent pixel centers are proposed. Using such an initialization for distance calculations, a generalization of the chamfer distance calculation is developed. The generalization allows the simultaneous calculation of distances within the object and its background by two consecutive chamfering processes. The performances of a number of variants of the methods are evaluated. It is shown that the shape-based interpolation using a near-optimal 3*3 distance and modified cubic spline between-slice interpolation has superior properties to previously proposed methods for estimating object locations in missing slices in tomographic radiology.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>

The Australian National Genomic Information Service, ANGIS, is accessible over the Australian Academic and Research Network, Australia's X.25 facility, and the switched telephone service. Three interfaces can be used: command driven, a CURSES based 2D menu system, and an X Windows system. Some 20 databases and over 400 applications are maintained. Sequence databases received as flat files are reduced to a common format and reindexed. They are updated either weekly or as often as new releases become available. The GenBank relational database is updated remotely from the Los Alamos National Laboratory daily and made available to users via a front end application. Analytical software consists of programs written in-house, and obtained elsewhere. The system was designed to integrate a disparate collection, modifications being made as required.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>