Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutationsAmit V. Khera, Sekar Kathiresan, Mark Chaffin et al.|Nature Genetics|2018Cited by 3.1k
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary DiseaseAmit V. Khera, Sekar Kathiresan, Connor A. Emdin et al.|New England Journal of Medicine|2016Cited by 1.5k
Whole-Genome Sequencing to Characterize Monogenic and Polygenic Contributions in Patients Hospitalized With Early-Onset Myocardial InfarctionAmit V. Khera, Sekar Kathiresan|Circulation|2019Cited by 327
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scoresOmer Weissbrod, Alkes L. Price, Yoshinori Murakami et al.|Nature Genetics|2022Cited by 279
Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery DiseaseKrishna G. Aragam, Pradeep Natarajan, Amanda Dobbyn et al.|Journal of the American College of Cardiology|2020Cited by 146