Recruitment and retention of underrepresented populations in Alzheimer's disease research: A systematic reviewAndrea Gilmore‐Bykovskyi, Yuanyuan Jin, Carey E. Gleason et al.|Alzheimer s & Dementia Translational Research & Clinical Interventions|2019 INTRODUCTION: Alzheimer's disease and related dementias (ADRD) disproportionately impact racial and ethnic minority and socioeconomically disadvantaged adults. Yet, these populations are significantly underrepresented in research. METHODS: We systematically reviewed the literature for published reports describing recruitment and retention of individuals from underrepresented backgrounds in ADRD research or underrepresented participants' perspectives regarding ADRD research participation. Relevant evidence was synthesized and evaluated for quality. RESULTS: We identified 22 eligible studies. Seven studies focused on recruitment/retention approaches, all of which included multifaceted efforts and at least one community outreach component. There was considerable heterogeneity in approaches used, specific activities and strategies, outcome measurement, and conclusions regarding effectiveness. Despite limited use of prospective evaluation strategies, most authors reported improvements in diverse representation in ADRD cohorts. Studies evaluating participant views focused largely on predetermined explanations of participation including attitudes, barriers/facilitators, education, trust, and religiosity. Across all studies, the strength of evidence was low. DISCUSSION: Overall, the quantity and quality of available evidence to inform best practices in recruitment, retention, and inclusion of underrepresented populations in ADRD research are low. Further efforts to systematically evaluate the success of existing and emergent approaches will require improved methodological standards and uniform measures for evaluating recruitment, participation, and inclusivity.
Relationship between resilience and self‐care in people with chronic conditions: A systematic review and meta‐analysisYuanyuan Jin, Muna Bhattarai, Wan‐chin Kuo et al.|Journal of Clinical Nursing|2022 BACKGROUND: Living with chronic condition(s) is difficult, due in part to the complexities of effective disease self-care. Self-care has been considered a challenging process according to the literature which describes multiple barriers patients with chronic conditions experience. Resilience has the potential to buffer the adversities of daily self-care and maintain physical and emotional well-being. No systematic review and meta-analysis have been conducted to synthesise and quantify the relationship between resilience and self-care across chronic conditions. AIMS: (1) To examine how the definitions and measurements of self-care and resilience align with the middle-range theory of self-care of chronic illness (i.e. self-care maintenance, self-care monitoring, and self-care management) and 3 Rs of resilience process from the society-to-cells framework (i.e. resistance, recovery and rebound) across different chronic conditions; and (2) to examine whether and the degree to which resilience is correlated with self-care across different chronic conditions. DESIGN: Systematic review and meta-analysis, following PRISMA guidelines. METHODS: PubMed, CINAHL, SocINDEX and PsychINFO were searched for quantitative studies published from January 2000 through July 2020. Descriptive data were summarised using numerical counting to provide an overview of the study characteristics. Definitions and measurements of self-care and resilience were synthesised narratively based on self-care and resilience theories. Numerical data with Pearson's product-moment correlation among observational studies were examined using meta-analysis. RESULTS: This review included 20 articles, involving 9,269 individuals across 11 chronic conditions. Despite self-care and resilience being defined and operationalised in a variety of ways, most definitions shared some underlying core constructs. Meta-analysis showed a positive relationship between resilience and self-care across chronic conditions. Findings from interventional studies indicated a bidirectional relationship between resilience and self-care. CONCLUSIONS: Overall, resilience was positively associated with self-care in people with chronic conditions. Longitudinal and experimental studies are needed to better understand the causal relationship between resilience and self-care. RELEVANT TO CLINICAL PRACTICE: Resilience has the potential to buffer the adversities of daily self-care and maintain physical and emotional well-being. The positive relationship between resilience and self-care found in this review provides preliminary evidence for clinicians to not only focus on reducing barriers and risk factors of self-care but also to improve or increase patients' resilience through various evidence-based interventions.
The association between prenatal exposure to organochlorine pesticides and thyroid hormone levels in newborns in Yancheng, ChinaChengcheng Li, Yibin Cheng, Quan Tang et al.|Environmental Research|2014 3D porous gear-like copper oxide and their high electrochemical performance as supercapacitorsA facile and mild approach was used for the controlled synthesis of 3D porous gear-like CuO on a Cu substrate (PGC) based on annealing gear-like Cu(OH)2 (GC) at 200 °C in air. There are 3–10 edges that build up a gear-like structure and a huge number of holes formed on each edge. As an integrated nanostructure, the binder-free PGC can be used as a supercapacitors electrode (SC) directly. Due to its 3D porous structure and the highly conductive Cu substrate as a current collector, the integrated electrode exhibited excellent electrochemical properties. These were demonstrated by excellent specific capacitance as high as 348 F g−1 at a discharge current density of 1 A g−1, which corresponds to the energy density of 43.5 Wh kg−1. The electrochemical tests also showed that the as-synthesized PGC exhibited excellent cycling stability.
Microstructure and mechanical properties of AE42 rare earth-containing magnesium alloy prepared by friction stir processingYuanyuan Jin, Kuaishe Wang, Wen Wang et al.|Materials Characterization|2019