β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACERobert Vassar, Martin Citron, Janis Fuller et al.|Science|1999Cited by 3.8k
Energy Inhibition Elevates β-Secretase Levels and Activity and Is Potentially Amyloidogenic in APP Transgenic Mice: Possible Early Events in Alzheimer's Disease PathogenesisRodney A. Velliquette, Robert Vassar|Journal of Neuroscience|2005Cited by 252
The case for low-level BACE1 inhibition for the prevention of Alzheimer diseaseEric McDade, Stefan F. Lichtenthaler, Iryna Voytyuk et al.|Nature Reviews Neurology|2021Cited by 136
BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localizationBrian D. Hitt, Robert Vassar|Molecular Neurodegeneration|2010Cited by 98
The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanismsSidhanth Chandra, Robert Vassar|Molecular Neurodegeneration|2023Cited by 55