5-N-Acetylardeemin, a novel heterocyclic compound which reverses multiple drug resistance in tumor cells. II. Isolation and elucidation of the structure of 5-N-acetylardeemin and two congeners.A family of novel compounds has been detected and isolated following an assay for the attenuation of multiple drug resistance in tumor cells from the fermentation broth and mycelia of a strain of Aspergillus fischeri which we have designated var. brasiliensis. The structures of three components were determined employing 1-D and 2-D homonuclear and heteronuclear NMR spectroscopy and mass spectrometry. The structure of 5-N-acetylardeemin was confirmed by single crystal X-ray diffraction. These compounds are most closely structurally related to asperlicin E1).
Studies on Repository Compound Stability in DMSO under Various ConditionsTiacumicins, a novel complex of 18-membered macrolides. II. Isolation and structure determination.Jill E. Hochlowski, Sue Swanson, L. M. RANFRANZ et al.|The Journal of Antibiotics|1987 A novel complex of Gram-positive antibiotics has been isolated from the fermentation broth and mycelium of Dactylosporangium aurantiacum subsp. hamdenesis subsp. nov. The structures of these six compounds were deduced employing UV, MS, IR, and extensive 1D and 2D homonuclear and heteronuclear NMR experiments. Each component contained a highly unsaturated 18-membered macrolide ring. Components differed from one another by minor structural variations in the macrolide ring and by the number and esterification pattern of glycosidically bound sugars.
Metabolites of four nudibranchs of the genus HypselodorisJill E. Hochlowski, Roger P. Walker, Chris M. Ireland et al.|The Journal of Organic Chemistry|1982 ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetabolites of four nudibranchs of the genus HypselodorisJill E. Hochlowski, Roger P. Walker, Chris Ireland, and D. John FaulknerCite this: J. Org. Chem. 1982, 47, 1, 88–91Publication Date (Print):January 1, 1982Publication History Published online1 May 2002Published inissue 1 January 1982https://pubs.acs.org/doi/10.1021/jo00340a018https://doi.org/10.1021/jo00340a018research-articleACS PublicationsRequest reuse permissionsArticle Views297Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Norrisolide, a novel diterpene from the dorid nudibranch Chromodoris norrisiADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNorrisolide, a novel diterpene from the dorid nudibranch Chromodoris norrisiJill E. Hochlowski, D. John Faulkner, Gayle K. Matsumoto, and Jon ClardyCite this: J. Org. Chem. 1983, 48, 7, 1141–1142Publication Date (Print):April 1, 1983Publication History Published online1 May 2002Published inissue 1 April 1983https://pubs.acs.org/doi/10.1021/jo00155a055https://doi.org/10.1021/jo00155a055research-articleACS PublicationsRequest reuse permissionsArticle Views277Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts