Cited by 601
Nebraska Medical Center
ORCID: 0000-0003-2655-4709Publishes on Sarcoma Diagnosis and Treatment, Bone Tumor Diagnosis and Treatments, Lymphoma Diagnosis and Treatment. 67 papers and 3.1k citations.
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The cytogenetic findings for two epithelioid hemangioendotheliomas are reported. An identical chromosomal translocation involving chromosomes 1 and 3 [t(1;3)(p36.3;q25)] was detected in both cases of epithelioid hemangioendothelioma, possibly representing a characteristic rearrangement for this histopathologic entity. The presence of clonal karyotypic abnormalities supports a neoplastic origin for the epithelioid variant of hemangioendothelioma. Identification of the 1;3 translocation may be useful diagnostically. Should additional studies confirm these data, this could lead to the identification of the gene(s) central to this neoplastic process.