Florian Nachon

Institut de Médecine Tropicale du Service de Santé des Armées

Publishes on Cholinesterase and Neurodegenerative Diseases, Computational Drug Discovery Methods, Pesticide Exposure and Toxicity. 259 papers and 8.1k citations.

PubIndex Score97Top 3%How it's scored

259Publications

8.1kTotal Citations

First publication: 1998First senior author: 2003

Cholinesterase and Neurodegenerative Diseases Computational Drug Discovery Methods Pesticide Exposure and Toxicity Chemical synthesis and alkaloids Pesticide and Herbicide Environmental Studies

Top publicationsby citations

Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase

Florian Nachon, Pierre‐Yves Renard, E. Carletti et al.|Biochemical Journal|2013

Cited by 461

Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

Guillaume Mercey, Pierre‐Yves Renard, Tristan Verdelet et al.|Accounts of Chemical Research|2012

Cited by 399

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study

Terrone L. Rosenberry, Florian Nachon|Molecules|2017

Cited by 285

Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure

Xavier Brazzolotto, Florian Nachon, M. Wandhammer et al.|FEBS Journal|2012

Cited by 114

First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase

Guillaume Mercey, Pierre‐Yves Renard, Tristan Verdelet et al.|Chemical Communications|2011

Cited by 103