Cell Signaling Technology

CRBN (D8H3S) Rabbit Monoclonal Antibody

#71810 · $169,998

67
Evidence Score · Well-Established
Used by 135 independent labs across 162 papers. How we score this →
29
Citing papers
697
Combined citations
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Research areas

Protein Degradation and Inhibitors19Ubiquitin and proteasome pathways11Multiple Myeloma Research and Treatments11Peptidase Inhibition and Analysis6Histone Deacetylase Inhibitors Research3Cholesterol and Lipid Metabolism3Cancer-related Molecular Pathways2Prostate Cancer Treatment and Research2

Papers citing this product

1
Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry
Nature Communications·2020·204 cit.·DOI
2
Preclinical Evaluation of Bavdegalutamide (ARV-110), a Novel PROteolysis TArgeting Chimera Androgen Receptor Degrader
Molecular Cancer Therapeutics·2024·66 cit.·DOI
3
Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation
Nature Communications·2023·58 cit.·DOI
4
Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders
Nature Communications·2021·53 cit.·DOI
5
The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling
Nature Communications·2021·42 cit.·DOI
6
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation
Nature Communications·2024·37 cit.·DOI
7
An IMiD-induced SALL4 degron system for selective degradation of target proteins
Communications Biology·2020·31 cit.·DOI
8
Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells
PLoS ONE·2015·27 cit.·DOI
9
Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader
Oncogene·2023·25 cit.·DOI
10
The TGFβ type I receptor kinase inhibitor vactosertib in combination with pomalidomide in relapsed/refractory multiple myeloma: a phase 1b trial
Nature Communications·2024·23 cit.·DOI

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