Cell Signaling Technology

AIM2 (D5X7K) Rabbit Monoclonal Antibody

#12948 · $157,348

65
Evidence Score · Well-Established
Used by 103 independent labs across 111 papers. How we score this →
83
Citing papers
2.8k
Combined citations
Supplier page Find this product

Research areas

Sirtuins and Resveratrol in Medicine14Calcium signaling and nucleotide metabolism7RNA modifications and cancer7Autophagy in Disease and Therapy7melanin and skin pigmentation5Biochemical and Molecular Research5Inflammasome and immune disorders5Cytokine Signaling Pathways and Interactions5

Papers citing this product

1
NAD <sup>+</sup> supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
Proceedings of the National Academy of Sciences·2018·457 cit.·DOI
2
Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity
Journal of Biological Chemistry·2020·196 cit.·DOI
3
Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells
Blood·2009·177 cit.·DOI
4
HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death
Cell Death and Disease·2016·158 cit.·DOI
5
De novo and salvage purine synthesis pathways across tissues and tumors
Cell·2024·155 cit.·DOI
6
Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich’s ataxia cardiomyopathy model
JCI Insight·2017·130 cit.·DOI
7
Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway
Oncotarget·2016·130 cit.·DOI
8
Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling
The Journal of Cell Biology·2011·98 cit.·DOI
9
JAK2 V617F Constitutive Activation Requires JH2 Residue F595: A Pseudokinase Domain Target for Specific Inhibitors
PLoS ONE·2010·85 cit.·DOI
10
Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis
Nature Communications·2023·74 cit.·DOI

Similar products

ProductVendorEvidencePricePapers
AIM2 AntibodyRabbitCell Signaling Technology65$31720
AIM2 (E5I8Z) Rabbit Monoclonal AntibodyRabbitCell Signaling Technology65$160,3518
Anti-AIM2 (N-terminal region) AntibodyRabbitPhosphoSolutions65——

Rate this reagent

Used this in your lab? Leave a quick rating. Reviews are anonymous and verified by academic email before they appear.

Your email is never shown publicly.