Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing

Mark B. Hampton(Christchurch Clinical Studies Trust), Anthony J. Kettle(Christchurch Clinical Studies Trust), Christine C. Winterbourn(Christchurch Clinical Studies Trust)
Cited by 1,417

Abstract

IN THE 1880s Elie Metchnikoff observed specialized phagocytic cells ingesting bacteria, and recognized the importance of phagocytosis as a defense mechanism in multicellular organisms.[1][1] Neutrophils are one of the professional phagocytes in humans. They ingest bacteria into intracellular


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