Chronic orexin receptor antagonism is associated with rescued sleep and agitation-like behaviour in tau transgenic PS19 mice, but sex-dependently improved cognition

Jarrah O.Z. Kron(Florey Institute of Neuroscience and Mental Health), L Jacobson, Leigh C. Walker(Florey Institute of Neuroscience and Mental Health), Daniël Hoyer(Complexity Science Hub), Jack G. Allocca, Heather Daykin(Florey Institute of Neuroscience and Mental Health), Jamie G. Elliot, Christie Ch’ng(Florey Institute of Neuroscience and Mental Health), Jeremy Metha, Ryan J. Keenan(The University of Melbourne), Terrance P. McDonald(Florey Institute of Neuroscience and Mental Health), Yasmin Potts(Florey Institute of Neuroscience and Mental Health)
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July 25, 2026
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