Dasatinib and quercetin senolytic treatment delays early onset intervertebral disc degeneration in SM/J mice
Emanuel J. Novais(Thomas Jefferson University), Makarand V. Risbud(Thomas Jefferson University)
Cited by 1
Related Papers
Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice
|Nature Communications|2021|413
TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc
|Journal of Biological Chemistry|2011|262
Inflammatory Cytokines Associated with Degenerative Disc Disease Control Aggrecanase-1 (ADAMTS-4) Expression in Nucleus Pulposus Cells through MAPK and NF-κB
|American Journal Of Pathology|2013|187
Hypoxic Regulation of Mitochondrial Metabolism and Mitophagy in Nucleus Pulposus Cells Is Dependent on HIF-1α–BNIP3 Axis
|Journal of Bone and Mineral Research|2020|127