Procalcitonin testing combined with NEWS2 evaluation compared with usual care based on NEWS2 for identification of sepsis and antibiotic initiation in the emergency department in England and Wales (PRONTO): a multicentre, randomised, controlled, open-label, phase 3 trial

Stacy Todd(University of Liverpool), Kerenza Hood(NHS Digital), Wakunyambo Maboshe(University Hospitals Sussex NHS Foundation Trust), Joanne Euden(University of Liverpool), Philip Pallmann(University of Liverpool), Andrew Tabner(University Hospitals of Derby and Burton NHS Foundation Trust), Martin Llewelyn(Brighton and Sussex Medical School), Neil French(University of Liverpool), Stephen Aston(University of Liverpool), Fiona McGill(Royal Liverpool and Broadgreen University Hospital NHS Trust), Matthew Inada-Kim(Cardiff University), Sarah Milosevic(Leeds Teaching Hospitals NHS Trust), Enitan D. Carrol(University of Liverpool), Julie Carman(University Hospital Southampton NHS Foundation Trust), Gavin Barlow(University of Liverpool), Alexandra Rollinson-Salter, Jennifer Condie(Cardiff University), Abin Thomas(University of Liverpool), Lucy Brookes-Howell(Hull York Medical School), Mahuampi Perez-Alijas, David Taylor-Robinson(Nottingham University Hospitals NHS Trust), Luke Vale(Cardiff University), Paul Schmidt(Sheikh Shakhbout Medical City), David Lugo Palacios(Sheikh Shakhbout Medical City), Stephanie Gilbert(University of Liverpool), Emma Thomas-Jones(Cardiff University), Jackie Hughes(Cardiff University), Philip Howard(Cardiff University), Lena Meister, Sam Clarkstone(Cardiff University), Gabriella Culina-Jones, Emmanuel Nsutebu(Cardiff University), Ingeborg D Welters(Cardiff University)
The Lancet Respiratory Medicine
March 22, 2026
Cited by 1


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