MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants
Aqfan Jamaluddin(University of Birmingham), Caroline M. Gorvin(Oxford Centre for Diabetes, Endocrinology and Metabolism)
Cited by 1
Related Papers
A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin–biased signaling
|Science Signaling|2018|43
MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants
|bioRxiv (Cold Spring Harbor Laboratory)|2025|1
Loss of phosphorylation sites required for β-arrestin recruitment in the calcium-sensing receptor cytoplasmic region may contribute to hypocalcemia
|bioRxiv (Cold Spring Harbor Laboratory)|2026|0