Asymmetric Synthesis of KRAS G12C Inhibitor MK-1084 via a Crystallization-Induced Diastereomer Transformation (CIDT)
Hongming Li(University of Pennsylvania), Jingjun Yin(Merck & Co., Inc., Rahway, NJ, USA (United States)), Christopher C. Nawrat(Merck & Co., Inc., Rahway, NJ, USA (United States)), Xin Wen(Merck & Co., Inc., Rahway, NJ, USA (United States)), Kai‐Jiong Xiao(Merck & Co., Inc., Rahway, NJ, USA (United States)), Gao Shang(Merck & Co., Inc., Rahway, NJ, USA (United States)), Yu‐hong Lam(Merck & Co., Inc., Rahway, NJ, USA (United States)), Eugene E. Kwan(Merck & Co., Inc., Rahway, NJ, USA (United States)), Zhiyan Song(Merck & Co., Inc., Rahway, NJ, USA (United States)), Jongrock Kong(Merck & Co., Inc., Rahway, NJ, USA (United States)), Zhiguo J. Song(Merck & Co., Inc., Rahway, NJ, USA (United States)), Matthew L. Maddess(Merck & Co., Inc., Rahway, NJ, USA (United States)), Xu Jj(Merck & Co., Inc., Rahway, NJ, USA (United States)), Heather C. Johnson(Merck & Co., Inc., Rahway, NJ, USA (United States)), Aaron C. Sather(Merck & Co., Inc., Rahway, NJ, USA (United States)), Jonathan M. E. Hughes(Merck & Co., Inc., Rahway, NJ, USA (United States)), Lushi Tan(Merck & Co., Inc., Rahway, NJ, USA (United States)), Jin Zhang(Pharmaron (United Kingdom)), Yongpeng Yuan, B. Wan(Shanghai Institute of Pharmaceutical Industry), Chao Fan(Pharmaron (United Kingdom)), Yonggang Chen(Merck & Co., Inc., Rahway, NJ, USA (United States)), Cyndi Qixin He(Merck & Co., Inc., Rahway, NJ, USA (United States)), Guiquan Liu(Shanghai Institute of Pharmaceutical Industry), Kevin M. Belyk(Merck & Co., Inc., Rahway, NJ, USA (United States))
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