Improved protein binder design using β-pairing targeted RFdiffusion

Isaac Sappington(University of Washington), David Baker(Howard Hughes Medical Institute), Cynthia S. Hinck(University of Pittsburgh), Steven M. Banik(Stanford University), Buwei Huang(University of Washington), Stephanie A. Robinson(Stanford University), Martin Toul(Ghent University), Andrew P. Hinck(University of Pittsburgh), Dionne Vafeados(University of Washington), Timothy P. Jenkins(Technical University of Denmark), Jeremiah Nelson Sims(University of Washington), Susana Vázquez Torres(University of Washington), Christopher J. Kim(University of Washington), Inna Goreshnik(Howard Hughes Medical Institute), Matthias Glögl(University of Washington), Savvas N. Savvides(Ghent University), Clara McCurdy(University of Washington), Xinru Wang(University of Washington), Tung Ching Chan(University of Washington), Mariana Garcia-Sanchez(University of Washington), Nicole Roullier(University of Washington), Nic Buchholz(University of Washington), Kenneth Verstraete(Ghent University), Hannele Ruohola-Baker(University of Washington), David S. Lee(University of Washington), Melisa Benard-Valle(Technical University of Denmark), Joseph L. Watson(University of Washington), Koen H. G. Verschueren(Ghent University), Brian Coventry(University of Washington)
Nature Communications
January 10, 2026
Cited by 3


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