Nanoengineered 3D culture substrate enables superior persistence and polyclonal engraftment of genetically engineered hematopoietic stem cells

Federico Midena(The San Raffaele Telethon Institute for Gene Therapy), Edoardo Carsana(The San Raffaele Telethon Institute for Gene Therapy), Martina Fiumara(Vita-Salute San Raffaele University), Chiara Brombin(Vita-Salute San Raffaele University), Fabrizio Benedicenti(The San Raffaele Telethon Institute for Gene Therapy), Sergio Arévalo(The San Raffaele Telethon Institute for Gene Therapy), Teresa Tavella(The San Raffaele Telethon Institute for Gene Therapy), Dafne Barozzi(Vita-Salute San Raffaele University), Samuele Ferrari(Vita-Salute San Raffaele University), Ivan Merelli(The San Raffaele Telethon Institute for Gene Therapy), Kety Giannetti(The San Raffaele Telethon Institute for Gene Therapy), Federica Cugnata(Vita-Salute San Raffaele University), Emanuela Jacchetti(Politecnico di Milano), Andrea Brendolan(Stanford Medicine), Giulio Cerullo(Istituto Nazionale per la Fisica della Materia), Cristina Scielzo(IRCCS Ospedale San Raffaele), Claudio Conci(Politecnico di Milano), Manuela Teresa Raimondi(Politecnico di Milano), Erika Zonari(The San Raffaele Telethon Institute for Gene Therapy), Eugenio Montini(The San Raffaele Telethon Institute for Gene Therapy), Luigi Naldini(University of Turin), Lucrezia della Volpe(The San Raffaele Telethon Institute for Gene Therapy), Marina Radrizzani(The San Raffaele Telethon Institute for Gene Therapy), Laura Alessandrini(Vita-Salute San Raffaele University), Francesco Gazzo(The San Raffaele Telethon Institute for Gene Therapy), Matteo Barcella(The San Raffaele Telethon Institute for Gene Therapy), Giacomo Farina(The San Raffaele Telethon Institute for Gene Therapy), Leonardo Cherubin(Politecnico di Milano), Martina Franchino(Vita-Salute San Raffaele University), Federico Fraschetta(Vita-Salute San Raffaele University), Alessandro Aiuti(Vita-Salute San Raffaele University), Roberta Vacca(The San Raffaele Telethon Institute for Gene Therapy), Roberto Osellame(Center for Biomolecular Nanotechnologies), Bernhard Gentner(The San Raffaele Telethon Institute for Gene Therapy), Francesca Ferrua(The San Raffaele Telethon Institute for Gene Therapy)
Cell stem cell
January 8, 2026
Cited by 2


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