A novel ligustrazine-based nanodelivery system protects against doxorubicin-induced cardiotoxicity by targeting the SIRT5–DUSP1 axis for mitochondrial repair

Hongshuo Shi(Shandong University of Traditional Chinese Medicine), Xing Chang(Chinese Academy of Medical Sciences & Peking Union Medical College), Guobin Liu(Shuguang Hospital), You Yang(Huazhong University of Science and Technology), Zhijiang Guo(Chinese Academy of Medical Sciences & Peking Union Medical College), Fenglei Zhang(Wenzhou Medical University), Man Zheng(Wenzhou Medical University), Jianxiao Liang(Shandong Provincial Hospital), Yifeng Nie(National Center for Nanoscience and Technology), Wenshi Xu(Shanghai University of Traditional Chinese Medicine), Boxian Pang(National Center for Nanoscience and Technology)
Journal of Nanobiotechnology
October 15, 2025
Cited by 45


Related Papers