Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons

Shuai Jin(Chinese Academy of Sciences), Caixia Gao(Sichuan Agricultural University), Shouyue Zhang(Center for Life Sciences), Guanglei Yang(Institute of Genetics and Developmental Biology), Danyuan Li(Center for Life Sciences), Yijing Liu(National Institutes of Health), Yuanqing Li(Institute of Genetics and Developmental Biology), Zhiheng Cheng(Institute of Genetics and Developmental Biology), Kevin T. Zhao(Broad Institute), Yingfeng Luo(Institute of Mechanics), Yong E. Zhang(University of Chicago), Junjie Liu(King Center), Rui Zhang(Chinese Academy of Sciences), Hongchao Li(Chinese Academy of Sciences), Yunjia Li(Beijing Institute of Genomics), Qiang Gao(State Key Laboratory of Plant Genomics), Jin‐Long Qiu(Institute of Mechanics), Ronghong Liang(Chinese Academy of Sciences)
Cell
September 29, 2025
Cited by 7


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