Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles

Yi Lin; Mengyao Li; Zijin Luo; Yanan Meng; Yan Zong; Hongyu Ren; Xiaolu Yu; Xiaoqiong Tan; Fan Liu; Tuo Wei; Qiang Cheng

doi:10.1038/s41563-025-02320-9

Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles

Yi Lin(Peking University), Mengyao Li(Chinese Academy of Sciences), Zijin Luo(Chinese Academy of Sciences), Yanan Meng(Chinese Academy of Sciences), Yan Zong(Peking University), Hongyu Ren(Chinese Academy of Sciences), Xiaolu Yu(Chinese Academy of Sciences), Xiaoqiong Tan(Peking University), Fan Liu(Chinese Academy of Sciences), Tuo Wei(Chinese Academy of Sciences), Qiang Cheng(Peking University)

Nature Materials

September 1, 2025

10.1038/s41563-025-02320-9

Cited by 29

Abstract

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