The deacetylases HDAC1/HDAC2 control JAK2V617F-STAT signaling through the ubiquitin ligase SIAH2

Al‐Hassan M. Mustafa(Johannes Gutenberg University Mainz), Oliver H. Krämer(Johannes Gutenberg University Mainz)

Signal Transduction and Targeted Therapy

August 28, 2025

10.1038/s41392-025-02369-7

Cited by 3

Related Papers

Histone deacetylase inhibitors dysregulate DNA repair proteins and antagonize metastasis-associated processes

|Journal of Cancer Research and Clinical Oncology|2020|55

SIAH2 antagonizes TYK2-STAT3 signaling in lung carcinoma cells

|Oncotarget|2014|37

HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1

|Cancers|2019|34

Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells

|Oncotarget|2018|29

The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil

|Cell Biology and Toxicology|2022|16