The GSA Family in 2025: A Broadened Sharing Platform for Multi-omics and Multimodal Data

Sisi Zhang(Chinese Academy of Sciences), Xu Chen(Chinese Academy of Sciences), Enhui Jin(Chinese Academy of Sciences), Anke Wang(Chinese Academy of Sciences), Tingting Chen(Chinese Academy of Sciences), Xiaolong Zhang(Chinese Academy of Sciences), Junwei Zhu(Chinese Academy of Sciences), Lili Dong(Chinese Academy of Sciences), Yanling Sun(Chinese Academy of Sciences), Caixia Yu(Chinese Academy of Sciences), Yubo Zhou(Chinese Academy of Sciences), Zhuojing Fan(Chinese Academy of Sciences), Huanxin Chen(Chinese Academy of Sciences), Shuang Zhai(Chinese Academy of Sciences), Yubin Sun(Chinese Academy of Sciences), Qiancheng Chen(Chinese Academy of Sciences), Jingfa Xiao(Chinese Academy of Sciences), Shuhui Song(Chinese Academy of Sciences), Zhang Zhang(Chinese Academy of Sciences), Yīmíng Bào(Chinese Academy of Sciences), Yanqing Wang(Chinese Academy of Sciences), Wenming Zhao(Chinese Academy of Sciences)
Genomics Proteomics & Bioinformatics
August 1, 2025
10.1093/gpbjnl/qzaf072
Cited by 166Open Access
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Abstract

The Genome Sequence Archive family (GSA family) provides a comprehensive suite of database resources for archiving, retrieving, and sharing multi-omics data for the global academic and industrial communities. It currently comprises four distinct database members: the Genome Sequence Archive (GSA, https://ngdc.cncb.ac.cn/gsa), the Genome Sequence Archive for Human (GSA-Human, https://ngdc.cncb.ac.cn/gsa-human), the Open Archive for Miscellaneous Data (OMIX, https://ngdc.cncb.ac.cn/omix), and the Open Biomedical Imaging Archive (OBIA, https://ngdc.cncb.ac.cn/obia). Compared to its 2021 version, the GSA family has expanded significantly by introducing a new repository, the OBIA, and by comprehensively upgrading the existing databases. Notable enhancements to the existing members include broadening the range of accepted data types, strengthening quality control systems, improving the data retrieval system, and refining data-sharing management mechanisms.

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