Durable response to CAR T is associated with elevated activation and clonotypic expansion of the cytotoxic native T cell repertoire

Giulia Cheloni(Tumour Institute of Tuscany), David Avigan(Beth Israel Deaconess Medical Center), Mike Mattie, Eleni Kanata(Broad Institute), Gayatri Tiwari, Ioannis S. Vlachos(Broad Institute), Kathrine S Rallis(Beth Israel Deaconess Medical Center), Jacalyn Rosenblatt(Beth Israel Deaconess Medical Center), Jenny Kim, Yered Pita-Juárez(Broad Institute), Georges Chedid(Beth Israel Deaconess Medical Center), Zachary M. Avigan(Icahn School of Medicine at Mount Sinai), Isabella Saldarriaga(Beth Israel Deaconess Medical Center), Daniela Torres(Beth Israel Deaconess Medical Center), Brodie Miles(Children's Cancer Therapy Development Institute), Jessica Liegel(Beth Israel Deaconess Medical Center), Dimitra Karagkouni(University of Thessaly)
Nature Communications
May 23, 2025
Cited by 18


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