Logic-gated biolaser for digital biochemical sensing
X. Jessie Yang(University of Electronic Science and Technology of China), Chenxiang Wang(University of Electronic Science and Technology of China), Zekai Li(University of Electronic Science and Technology of China), Tingting Wang(University of Electronic Science and Technology of China), Cairong Zhang(University of Electronic Science and Technology of China), Mateusz Śmietana(Warsaw University of Technology), Yunjiang Rao(University of Electronic Science and Technology of China), Yuan Gong(University of Electronic Science and Technology of China)
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Abstract
We report a digital biosensor with the logic gate in an optical fiber microcavity. The logic gate is controlled by analyte-induced DNA conformation changes, switching laser emission through the FRET effect. Logic gates of OR and INHIBIT are demonstrated for digital biosensing with a wide threshold range, about one order of magnitude higher than fluorescence.
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