Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis

Malgorzata Gozdecka(Wellcome Sanger Institute), George S. Vassiliou(Wellcome/MRC Cambridge Stem Cell Institute), Konstantinos Tzelepis(Wellcome/MRC Cambridge Stem Cell Institute), Theodoros Georgomanolis(Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases), Pedro M. Quirós(Universidad de Oviedo), Vijaya Baskar Mahalingam Shanmugiah(Wellcome/MRC Cambridge Stem Cell Institute), Christian Frezza(Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases), George Giotopoulos(Wellcome/MRC Cambridge Stem Cell Institute), Paolo Gallipoli(Wellcome/MRC Cambridge Stem Cell Institute), James A. Nathan(University of Cambridge), Ludovica Marando(Wellcome/MRC Cambridge Stem Cell Institute), Guinevere L. Grice(University of Cambridge), Rula Bany Bakar(MRC Epidemiology Unit), Brian J.P. Huntly(Wellcome/MRC Cambridge Stem Cell Institute), Richard J Stopforth(MRC Epidemiology Unit), Aristi Damaskou(Wellcome/MRC Cambridge Stem Cell Institute), Rachael Wilson(Wellcome/MRC Cambridge Stem Cell Institute), Clea Bárcena(Universidad de Oviedo), Justyna Rak(Wellcome/MRC Cambridge Stem Cell Institute), William G. Dunn(Wellcome/MRC Cambridge Stem Cell Institute), Ryan Asby(Wellcome/MRC Cambridge Stem Cell Institute), Penny Wright(Canterbury Health Laboratories), Arthur Kaser(University of Cambridge), Margarete A. Fabre(AstraZeneca (United Kingdom)), Eliza Yankova(Wellcome/MRC Cambridge Stem Cell Institute), Muxin Gu(Wellcome/MRC Cambridge Stem Cell Institute), Graham Duddy(The Francis Crick Institute), Annalisa Mupo(Wellcome Sanger Institute), Monika Dudek(Wellcome/MRC Cambridge Stem Cell Institute), Siddhartha Kar(University of Cambridge), Nisha Narayan(Wellcome/MRC Cambridge Stem Cell Institute), Paul Carter(University of Cambridge), Dean C. Pask(Wellcome/MRC Cambridge Stem Cell Institute), Sean Wen(Wellcome/MRC Cambridge Stem Cell Institute), Slavé Petrovski(AstraZeneca (United Kingdom)), Laura Bond(Wellcome/MRC Cambridge Stem Cell Institute), Jonathan Mitchell(AstraZeneca (Australia)), A. Ramesh(Wellcome/MRC Cambridge Stem Cell Institute), Jonathan Cooper(Wellcome Sanger Institute), Sarah J. Horton(Wellcome/MRC Cambridge Stem Cell Institute), Matthew McLoughlin(Wellcome/MRC Cambridge Stem Cell Institute), Kosuke Yusa(Kyoto University)
Nature
April 16, 2025
Cited by 34


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