Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population

Yuanjun Gu; Hilary C. Martin; Adam Pavlinek; Richard A. I. Bethlehem; Ole Mors; Daniel H. Geschwind; Marcin A. Radecki; Rafael Romero-García; Laura Sichlinger; David M. Greenberg; Anders D. Børglum; Merete Nordentoft; Alexandra Havdahl; Xinhe Zhang; Lucia Dutan Polit; Meng‐Chuan Lai; David H. Rowitch; Jonathan Mill; Jakob Grove; Thomas Werge; Jonas Bybjerg‐Grauholm; Saashi A. Bedford; Elizabeth Weir; Deep Adhya; Carrie Allison; Florina Uzefovsky; Eva-Maria Stauffer; Matthew E. Hurles; Alex Tsompanidis; Alexander Heazell; Rosemary Holt; Madeline A. Lancaster; Alice Franklin; Lidia V. Gabis; Yumnah Khan; Kathy K. Niakan; Michael Lombardo; Preben Bo Mortensen; José M. González; Jonathan Davies; Tal Biron-Shental; David M. Hougaard; Graham J. Burton; Rosie Bamford; Deepak Srivastava; Bonnie Ayeung; Joanna Davis

doi:10.1038/s41380-025-02927-z

Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population

Yuanjun Gu(University of Cambridge), Hilary C. Martin(Wellcome Sanger Institute), Adam Pavlinek(King's College London), Richard A. I. Bethlehem(MRC Cognition and Brain Sciences Unit), Ole Mors(Aarhus University), Daniel H. Geschwind(University of California, Los Angeles), Marcin A. Radecki(IMT School for Advanced Studies Lucca), Rafael Romero-García(University of Cambridge), Laura Sichlinger(King's College London), David M. Greenberg(Bar-Ilan University), Anders D. Børglum(Aarhus University), Merete Nordentoft(University of Copenhagen), Alexandra Havdahl(Norwegian Institute of Public Health), Xinhe Zhang(University of Cambridge), Lucia Dutan Polit(King's College London), Meng‐Chuan Lai(University of Cambridge), David H. Rowitch(University of California, San Francisco), Jonathan Mill(King's College London), Jakob Grove(Aarhus University), Thomas Werge(Sankt Hans Hospital), Jonas Bybjerg‐Grauholm(Statens Serum Institut), Saashi A. Bedford(University of Cambridge), Elizabeth Weir(University of Cambridge), Deep Adhya(Wellcome/MRC Cambridge Stem Cell Institute), Carrie Allison(University of Cambridge), Florina Uzefovsky(Ben-Gurion University of the Negev), Eva-Maria Stauffer(University of Cambridge), Matthew E. Hurles(Wellcome Sanger Institute), Alex Tsompanidis(University of Cambridge), Alexander Heazell(Manchester Academic Health Science Centre), Rosemary Holt(University of Cambridge), Madeline A. Lancaster(MRC Laboratory of Molecular Biology), Alice Franklin(University of Exeter), Lidia V. Gabis(Maccabi Healthcare Services), Yumnah Khan(University of Cambridge), Kathy K. Niakan(University of Cambridge), Michael Lombardo(University of Cambridge), Preben Bo Mortensen(Aarhus University), José M. González(Spanish National Cancer Research Centre), Jonathan Davies(University of Exeter), Tal Biron-Shental(Tel Aviv University), David M. Hougaard(Statens Serum Institut), Graham J. Burton(University of Cambridge), Rosie Bamford(University of Exeter), Deepak Srivastava(University of California, San Francisco), Bonnie Ayeung(University of Cambridge), Joanna Davis(University of Cambridge)

Molecular Psychiatry

February 24, 2025

10.1038/s41380-025-02927-z

Cited by 6

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