Safety, tolerability, pharmacokinetics, and neutralisation activities of the anti-HIV-1 monoclonal antibody PGT121.414.LS administered alone and in combination with VRC07-523LS in adults without HIV in the USA (HVTN 136/HPTN 092): a first-in-human, open-label, randomised controlled phase 1 trial
Srilatha Edupuganti(Emory University), Bethany Coomes, David C. Montefiori(Duke University), Yunda Huang(Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa), Maurine D. Miner(Fred Hutch Cancer Center), Marc Siegel(George Washington University), Christopher B. Hurt(University of North Carolina at Chapel Hill), Bob C. Lin(National Institutes of Health), Marianne Gildea, Bette Korber(Los Alamos National Laboratory), Stephen R. Walsh(Beth Israel Deaconess Medical Center), Kenneth H. Mayer(Miriam Hospital), Michael Pensiero(National Institute of Allergy and Infectious Diseases), Hans Spiegel(Aaron Diamond AIDS Research Center), Estelle Piwowar‐Manning(Johns Hopkins University), Georgia D. Tomaras(National Institutes of Health), Kathryn E. Stephenson(Beth Israel Deaconess Medical Center), Maija Anderson(Fred Hutch Cancer Center), Zonglin He(Jinan University), Nadine Rouphael(Emory University), Bonnie J. Dye(Family Health International 360), Raphael J. Landovitz(APLA Health), Cassie Grimsley Ackerley, Catherine Yen(National Institutes of Health), Kshitij Wagh(Los Alamos National Laboratory), Dan H. Barouch(Beth Israel Deaconess Medical Center), Jonathan Lucas(Family Health International 360), Theresa Gamble(University of Utah), Chenchen Yu(Fred Hutch Cancer Center), Lúcio Gama(National Institutes of Health), Daniel S. Graciaa(Emory University), Jack Heptinstall(Duke University), Margaret E. Ackerman(Dartmouth College), Carmen A. Paez(Fred Hutch Cancer Center), Colleen F. Kelley(Emory University), Stephanie Regenold(National Institute of Allergy and Infectious Diseases), Brett Hanscom(Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa), Nicole A. Doria‐Rose(National Institutes of Health), Nandini Sane, Magdalena E. Sobieszczyk(Columbia University Irving Medical Center), Elizabeth Domin(Duke University), Sharon Curate-Ingram, Michelle Robinson(University College London), Jennifer Grossman(University of Calgary), Krisha McKee(National Institutes of Health), Nadia McClosky(Fred Hutch Cancer Center), Amber Babinec, Lily Zhang(Fred Hutch Cancer Center), Kelly E. Seaton(International Vaccine Institute)
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